Tokyo was suddenly assaulted by the Great Collapse! The moment they heard it, everyone in the city fell into a coma. When they awoke, Tokyo was enveloped in a red mist. Though some plotted to escape, not a single person has made it through the red mist alive, and Tokyo has become inaccessible. Tokyo is now a shadowy and inaccessible city from which there is no escape! Five months later, the very last person still in a coma, univeristy student Kamina Chihiro awakens, and curtains rise on the fierce Vermillion legend! (thetvdb.com)